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Indapamide
Indapamide
Indapamide
Indapamide
Indapamide
Indapamide

26807-65-8

Price USD45.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:9000kg/per week
  • Time:2022-05-20

Product Details

  • Product NameIndapamide
  • CAS No.26807-65-8
  • EINECS No.248-012-7
  • MFC16H16ClN3O3S
  • MW365.83
  • AppearanceneatWhite to Off-White
  • Melting point 160-162°C
  • storage temp. -20°C Freezer
  • Water Solubility Soluble in ethanol. Insoluble in water
  • Boiling point 110.4°C (rough estimate)
  • density 1.2895 (rough estimate)
Product nameIndapamide
CAS26807-65-8
Appearancewhite powder
Assay99%
StorageCool and Protect from light


Indapamide has a dual effect of diuretic and calcium antagonism, by inhibiting Na+ reabsorption at the proximal end of distal convoluted tubules, diuretic effect, and blocking Ca2+ influx, high selectivity to vascular smooth muscle, so that peripheral small blood vessels dilate, producing antihypertensive effect. But the effect on vascular smooth muscle stronger diuretic effect, below the diuretic doses can step-down, higher doses showed diuretic effect, but no thiazide diuretic shortcomings, namely not cause orthostatic hypotension, flush and reflective tachycardia, on blood picture, metabolism of blood fat, sugar and renal function also had no obvious effect, therapeutic doses of heart rate, cardiac output, no significant changes in electrocardiogram (ecg) were It has no obvious effect on central nervous system and vegetative nervous system. The antihypertensive effect was observed for 2 ~ 3h after oral administration, and the effect remained for 24h. The diuretic effect appeared at 3h and reached its maximum effect at 4 ~ 6h. Different from other diuretics, this product is highly fat soluble. After oral absorption, it has the highest concentration in liver and kidney plasma, but low concentration in heart, lung, muscle and fat. This product is excreted mainly from the kidney as a metabolite and as a 5% prototype. Indapamide is suitable for mild and moderate primary hypertension, can also be used for congestive heart failure caused by water sodium retention, with renal failure are also applicable to the patients with high blood pressure, diabetes, hyperlipidemia, use antihypertensive effect is remarkable, and beta blockers used curative effect is better, because this drug has diuretic effect, can cause hypokalemia, can complement potassium at the same time.

Packaging & Shipping

Quantity(Metric Tons)1 - 12 - 20>20
Est. Time(days)1025To be negotiated


Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
 Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.



Company Profile Introduction

Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

 

  • Since:2021-03-01
  • Address: Room 1810, Future Time Business Building, 121 Zhongshan West Road, Qiaoxi Dist.
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