138402-11-6
| Price | USD100.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:9000kg/per week
- Time:2022-05-20
Product Details
- Product NameIrbesartan
- CAS No.138402-11-6
- EINECS No.604-078-2
- MFC25H28N6O
- MW428.53
- Appearancepowderwhite to off-white
- Melting point 180-181°C
- storage temp. 2-8°C
- Boiling point 648.6±65.0 °C(Predicted)
- density 1.30±0.1 g/cm3(Predicted)
| Product Name | Sitagliptin |
| CAS | 486460-32-6 |
| MF | C16H15F6N5O |
| MW | 407.3136 |
| Density | 1.61±0.1 g/cm3(Predicted) |
| Appearance | White Powder |
| Assay | 98%min |
Irbesartan is an Angiotensin ⅱ (Ang ⅱ) receptor inhibitor. The Angiotensin ⅱ receptor can be divided into AT1 and AT2. Irbesartan can inhibit the transformation of Ang ⅰ into Ang ⅱ by selectively blocking THE AT1 receptor of AnglI, and can specifically antagonize the Angiotensin converting enzyme 1 receptor (AT1). The antagonistic effect of AT1 is 8500 times that of AT2. By blocking the binding of Ang ⅱ to AT1 receptor selectively, the vasoconstriction and the release of aldosterone are inhibited, and the antihypertensive effect is produced. It does not inhibit angiotensin converting enzyme (ACE), renin, and other hormone receptors, nor does it inhibit ion channels involved in blood pressure regulation and sodium balance. Irbesartan also reduces electrical remodeling of the heart muscle, thus reducing mortality in hypertensive patients. Irbesartan is currently the most effective drug in the treatment of hypertension and cardiovascular diseases.
Function:
Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
Irbesartan is a nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.
Packaging & Shipping
| Quantity(Metric Tons) | 1 - 1 | 2 - 20 | >20 |
| Est. Time(days) | 10 | 25 | To be negotiated |
Company Information
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Our Services
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.
Company Profile Introduction
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ，that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
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- Since:2021-03-01
- Address: Room 1810, Future Time Business Building, 121 Zhongshan West Road, Qiaoxi Dist.