diltiazem hydrochloride
Price | USD10.00 |
Packge | 1KG |
- Min. Order:1KG
- Supply Ability:10T/month
- Time:2021-08-23
Product Details
- Product Namediltiazem hydrochloride
- CAS No.33286-22-5
- EINECS No.251-443-3
- MFC22H27ClN2O4S
- MW450.98
- AppearancePowderWhite to off-white
- storage temp. 2-8°C
- Water Solubility soluble
- Melting point 212-214 °C
- density 1.30 g/cm3
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Diltiazem is a calcium inflow inhibitor (slow channel blocker or calcium antagonist).
diltiazem hydrochloride
1 pharmacology this product is a calcium ion channel blocker, its effect is related to the inhibition of calcium ion flow in
cardiac and vascular smooth muscle depolarization.This product can effectively dilate the coronary artery of epicardium and
endocardium, relieve the spontaneous angina pectoris or angina pectoris caused by the coronary artery spasm induced by ergoxin.
Reduces myocardial oxygen demand by slowing heart rate and lowering blood pressure, increases exercise tolerance and relieves
exertional angina.This product can relax the vascular smooth muscle, reduce the peripheral vascular resistance, and reduce blood
pressure;The extent of its hypotension is related to the degree of hypertension.This product has negative inotropic effect and can
slow down the conduction of sa node and av node.
2. Toxicological carcinogenic, mutagenic and reproductive toxicity: it has been reported that rats have taken this product for 24
months, and mice have taken this product for 21 months without any carcinogenic effect.No mutagenic effect was found in vitro
bacterial experiments.Animal experiments have proved that this product has no obvious effect on fertility.
Physicochemical properties of diltiazem hydrochloride
Appearance description: odorless white powder
Index of refraction 118 ° (C=1, H2O)
Storage conditions
Seal and store at 2 C -8 C
The stability of
Stable under normal temperature and pressure
Water solubility soluble
Company Profile
Company Profile Introduction
shuoKang biotechnology co., LTD. Is located in wuhan, China, is a collection research and development, production,sales for the integration of medicine and chemical industry leader, pharmaceutical intermediates research and development qualifications, with advanced production equipment and professional research and development team,the company has been to high-quality products and services to Chinese and foreign customers ,Provide customers with a full range of services such as product procurement, research and development, quality control, logistics management, etc., and become a trusted partner of customers.
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- Since:2021-05-25
- Address: Room H05106, Building 1, No.58 Optics Valley Avenue, East Lake New Technology Development Zone, Wuha