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HomecompanyAtracurium Besylate
Atracurium Besylate

Atracurium Besylate

Price Get Latest Price
Packge 25Kg/Bag
  • Min. Order:2Kg/Bag
  • Supply Ability:20 tons
  • Time:2022-06-10

Product Details

  • Product NameAtracurium Besylate
  • CAS No.64228-81-5
  • EINECS No.264-743-4
  • MFC65H82N2O18S2
  • MW1243.48
  • Appearancepowderwhite
  • Melting point 85-90°C
  • storage temp. Inert atmosphere,2-8°C

Product Information

Product name

Atracurium Besylate

CAS No.

64228-81-5

Molecular Formula

C53H72N2O12.2(C6H5O3S)

Molecular Weight

257.60

Quality Standard

96% up by HPLC, GMP,USP

Appearance

White or almost white powder

Usage

Function of Atracurium Besylate

Atracurium besylate is a skeletal muscle relaxant for general anesthesia, suitable for the treatment of muscle relaxation for endotracheal intubation and for muscle relaxation required for thoracic and abdominal surgery. Like most neuromuscular blocking agents, it can Causes the release of histamine, skin flushing, transient hypotension, and occasionally bronchospasm. Caution should be used in patients with myasthenia gravis, neuromuscular disease, and severe electrolyte disturbances, as it potentiates the effects of other non-depolarizing agents. People with severe cardiovascular disease are more sensitive to the transient hypotensive reaction of this product, so it is recommended to give slow intravenous injection in divided doses.


COA of Atracurium Besylate

ITEMS

SPECIFICATION

RESULT

Appearance:

white or almost white powder,

slightly hygroscopic, ordorless

 

 Confirms

Very solutable in acetonitrile or chloroform, Soluble in Water, very soluble and practically insolutable in ethyl ether

 Confirms

Identification

(1) IR

Conforms

 (2) HPLC

Conforms

Water

≤ 5.0%

0.6%

Residue on ignition

≤ 0.2%

0.1%

Methyl benzenesulfonate

≤ 0.1%

Undetected

Toluene

≤ 890ppm (ICH)

102ppm

Chromatographic purity

(1) Laudanosine: ≤ 0.5%

(2) Other individual impurities: ≤ 1.0%

(3) Total Impurities: ≤ 3.5%

0.01%

0.38%

1.3%

Isomer Ratio

Trans-Trans Isomer: 5%-6.5%

5.7%


Cis-Trans Isomer: 34.5%-38.5%

36%


Cis-Cis Isomer: 55%-60%

58.2%

Assay

96%-102%

  (C65H82N2O18S2 on anhydrous basis)

100.2%

Residue Solvents

(1) Dichloromethane: ≤ 600ppm

(2) Acctonitrile: ≤ 410ppm

(3) Ethyl ether: ≤ 5000ppm

Undetected

Undetected

1739ppm

Result

Confirms to USP34


Company Information




Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.
  • Since:1996-07-16
  • Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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