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HomecompanyTop Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price
Isotretinoin
Isotretinoin
Isotretinoin
Isotretinoin
Isotretinoin
Isotretinoin

Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price

Price Get Latest Price
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:20 tons
  • Time:2021-12-01

Product Details

  • Product NameIsotretinoin
  • CAS No.4759-48-2
  • EINECS No.225-296-0
  • MFC20H28O2
  • MW300.44
  • AppearanceFine Crystalline PowderYellow-orange to orange
  • Melting point 172-175 °C (lit.)
  • storage temp. -20°C
  • Water Solubility insoluble
  • Boiling point 381.66°C (rough estimate)
  • density 1.0597 (rough estimate)

Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price



Isotretinoin Chemical Properties
Melting point 172-175 °C(lit.)
Boiling point 381.66°C (rough estimate)
density 1.0597 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. −20°C
solubility Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka4.76±0.33(Predicted)
form Fine Crystalline Powder
color Yellow-orange to orange
Water Solubility insoluble
λmax354nm(EtOH)(lit.)
Merck 14,5228
Stability:Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKeySHGAZHPCJJPHSC-YCNIQYBTSA-N
CAS DataBase Reference4759-48-2(CAS DataBase Reference)
EPA Substance Registry SystemIsotretinoin (4759-48-2)



Use of  Isotretinoin

Isotretinoin Descrption

Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.


Function:

Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy. 




Company Profile Introduction

Hebei Crovell Biotech Co., Ltd. was founded in 2019 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.



Our company has strong technical strength, advanced equipment, strict quality management system and high-quality aftersales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival. All for the customers’ satisfaction, all for the long term healthy development of the enterprise. In the past 2 more years, we have been strictly managing the whole trade process, focusing on every detail, providing customers with all-round services such as product purchase, R & D, quality control, logistics management and so on, and become  reliable cooperation company and partner for our clients. Nowadays We formed large varieties, large scale, complete categories, refined degree, added value and high technology content product chain .There are several series including pharmaceutical products, food grade additives, industrial grade, fertilizer grade and mineral products.


 

  • Since:2019-01-04
  • Address: 2-2-1901, Huachenglvzhou 1st Phase. No.169 Shengli Nan Street,Qiaoxi District ,Shijiazhuang city, H
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