Hydroxychloroquine sulfate CAS:747-36-4

Melting point 240℃

Storage conditions refrigerator

Solubility H2O: >20mg/mL

Form CrystallinePChemicalbookowder

Color white to off-white

Solubility FREELYSOLUBLE Merck 14,4818

Antimalarial drugs:

Hydroxychloroquine sulfate is an anti-malarial drug, which also has anti-inflammatory, immunomodulatory and anticoagulant effects. At present, hydroxychloroquine is mainly used in clinical treatment for rheumatoid arthritis, juvenile chronic arthritis, discoid lupus erythematosus and systemic erythema Lupus, but the clinical onset is slower, and it usually takes 2 to 4 months of Chemicalbook time. The pharmacological effects of this drug are not very clear. It may be related to stabilizing the lysosomal membrane, inhibiting the formation of prostaglandins, inhibiting the chemotaxis of polymorphonuclear cells and the effect of phagocytic cells, and may interfere with monocyte interleukin- 1. Formation and inhibition of neutrophil superoxide release.