Prednisolone-21-acetate CAS 52-21-1

English name: Prednisolone-21-acetate

English synonyms: PREDNISOLONEACETATE; PREDNISOLONE21-ACETATE; PRICORTIN; 1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL3,20-DIONE21-ACETATE;1,4-PREGNADIENE-Chemicalbook3,20-DIONE-11BETA,17ALPHA,21-TRIOL21 -ACETATE;1,4-PREGNADIEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE21-ACETATE;1,4-PREGNADIEN-11-BETA,17,21-TRIOL-3,20-DIONE21-ACETATE;1 -DEHYDROCORTISOL21-ACETATE

CAS Number: 52-21-1

Molecular formula: C23H30O6

Molecular weight: 402.48

EINECS number: 200-134-1

Function and use

Prednisolone acetate is a medium acting glucocorticoid. Its effect is the same as that of prednisone, and its curative effect is about the same as that of prednisone. It has strong anti-inflammatory effect and weak water and salt metabolism. This product is a hydroxyl compound (hydroxyl at the 11 position), local application has good curative effect, and is also suitable for patients with liver dysfunction. After oral administration, the chemicalbook was absorbed quickly and completely, reaching the peak of plasma concentration in one hour. The plasma protein binding rate was 90% ～ 95%, and the half-life was about 200 minutes. It can enter the fetal circulation, and the amount of drug appearing in the milk is 0.07% - 0.23%. It is metabolized in liver and excreted mainly from kidney, of which protodrug accounts for more than 20%.