Choline glycerophosphate.

• Hot sale alpha gpc / Choline glycerophosphate with best price CAS 28319-77-9

• Test items	Specification
  Description	White powder, Neutral odor, very highly hygroscopic.
  Identification(NMR)	Conforms to the standard
  Solubility(H2O, 10% w/v)	Clear
  Bulk Density (Untapped)	0.90g/cm3~1.08g/cm3
  Stability	Dry and light protected storage; Stable under normal usage.
  Color of solution	≤Y7
  Water content	≤2.0%
  pH	7.5~9.0
  Specific Rotation[α]25D	-2.4O~2.95O
  Related Substances (HPLC)	G.P.E. :<0.2%
  	Glycerophosric acid: <0.2%
  Related Substances(TLC)	Single spot
  Purity(by Titration) L-α-Glycerophosphoryl Choline	≥99.0%
  Solvents Residue(Ethanols)	≤1.0%

   

  L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a naturalcholine compound found in the brain and in milk. It is also a parasympathomimeticacetylcholine precursor which may have potential for the treatment of Alzheimer's disease and dementia. Alpha-GPC is also used as a nootropic dietary supplement to enhance memory and cognition.

  Function

  1. Increases human Growth Hormone (hGH)
  Increases in endogenous human Growth Hormone (hGH) secretion by the anterior pituitary in conjunction with Growth Hormone Releasing Hormone (GHRH); that is, both Alpha-GPC and GHRH act concertedly to stimulate the release of hGH, naturally;
  2. More strength from work-outs and training programs
  Acts as a precursor of acetylcholine (ACh); thus, Alpha-GPC activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis;
  3. Improved lipotrophic functions in the liver
  Elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions (methyl group transferases) in the liver. Research has shown that fatty liver, a condition associated with obesity, diabetes and heavy alcohol consumption, often leads to cirrhosis of the liver or liver failure. Studies conducted by Alan L. Buchman, M.D., associate professor of medicine at The Feinberg School of Medicine at Northwestern University, have shown that fatty liver can be prevented and possibly even eliminated with increased levels of choline. Alpha-GPC also acts synergistically with the body's store (and/or supplementation) of S-adenosyl-L-methionine (SAM or SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver;
  4. Improved balanced and coordination
  Produces improved balanced and coordination when combined with 'skill set' practice and training as a result of normalized nerve transmission in the brain, and in cardiac, skeletal and smooth muscles.

   

  Application

  Alpha GPC  rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.Alpha GPC is derived from highly purified soy lecithin by companies like Lipoid, VAV Life Sciences, Chemi SPA etc.

  Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer’s Disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.

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Packaging Details

25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients

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