5-Aminosalicylic Acid / Mesalamine / Mesalazine Powder

Factory Price 5-Aminosalicylic Acid Mesalamine Mesalazine Powder

Price	USD57.00
Packge	25KG

Min. Order:25KG
Supply Ability:200ton
Time:2022-07-14

Product Details

Product Name 5-Aminosalicylic Acid / Mesalamine / Mesalazine Powder
CAS No.89-57-6
EINECS No.201-919-1
MFC7H7NO3
MW153.14
InChIKeyKBOPZPXVLCULAV-UHFFFAOYSA-N
Appearancetabletsoff-white to gray
storage temp. 2-8°C
Melting point 275-280 °C (dec.) (lit.)
Water Solubility <0.1 g/100 mL at 21 ºC
Boiling point 276.03°C (rough estimate)
density 1.3585 (rough estimate)

5-Amino Salicylic Acid / 5-Aminosalicylic Acid Cas 89-57-6 Mesalamine Mesalazine Powder

Mesalazine (INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission in Crohn's disease.
It is sold in an oral form to maintain remission in Crohn's disease, and as a rectal suppository and an enema for the lower bowel conditions. It is generic and sold under many brand names worldwide, and there are many formulations.
There is no data on use in pregnant women, but the drug does cross the placenta and is excreted in breast milk. The drug should not be used in children under two, people with kidney disease, or people who are allergic to aspirin.
Side effects are primary gastrointestinal but may include headache; GI effects include nausea, diarrhoea and abdominal pain. There have been scattered reports of various problems when the oral form is used, including problems caused by myelosuppression (leukopenia, neutropenia, agranulocytosis, aplastic anaemia, and thrombocytopenia, as well as hair loss, peripheral neuropathy, pancreatitis, liver problems, myocarditis and pericarditis, allergic and fibrotic lung reactions, lupus erythematosus-like reactions and rash (including urticaria), drug fever, interstitial nephritis and nephrotic syndrome, usually reversible on withdrawal. Very rarely, use of mesalazine has been associated with an exacerbation of the symptoms of colitis, Stevens Johnson syndrome and erythema multiforme.
Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine. It is also the active component of the prodrug balsalazide along with the inert carrier molecule 4-aminobenzoyl-beta-alanine.

Chemical Name	mesalamine
Synonyms	Mesalazine;5-AMINO SALICYLIC ACID;2-Cyanobenzoic acid;Benzoic acid, 5-amino-2-hydroxy-;5-AMINO-2-HYDROXYBENZOIC ACID FOR SYNTHESIS;Expand
CAS No.	89-57-6
Molecular Formula	C7H7NO3
Molecular Weight	153.13500
PSA	83.55000
LogP	1.25380

Company Profile Introduction

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate,carbopol and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.