CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
---|---|
Boiling Point | 417.9 |
Melting Point | 205 |
Solubility | 0.63% |
LogP | 5.9 |
Dissociation Constants | 7.05 |
Collision Cross Section | 187.2 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 291.4 g/mol |
---|---|
XLogP3 | 5.6 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 1 |
Rotatable Bond Count | 5 |
Exact Mass | 291.198699802 g/mol |
Monoisotopic Mass | 291.198699802 g/mol |
Topological Polar Surface Area | 3.2 Ų |
Heavy Atom Count | 22 |
Formal Charge | 0 |
Complexity | 428 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 1 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. Common side effects when taken by mouth include nausea, diarrhea, headache, cough, rash, and elevated liver enzymes.Severe side effects include liver problems and allergic reactions.