84057-95-4
Product Name:
Ropivacaine
Formula:
C17H26N2O
Synonyms:
(2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide;Ropivacaine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Solubility | 53.8 mg/mL |
LogP | 2.9 |
Dissociation Constants | 8.07 |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H336:Specific target organ toxicity,single exposure; Narcotic effects H370:Specific target organ toxicity, single exposure |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. |
COMPUTED DESCRIPTORS
Molecular Weight | 274.4 g/mol |
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XLogP3 | 2.9 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 4 |
Exact Mass | 274.204513457 g/mol |
Monoisotopic Mass | 274.204513457 g/mol |
Topological Polar Surface Area | 32.3 Ų |
Heavy Atom Count | 20 |
Formal Charge | 0 |
Complexity | 308 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
(S)-ropivacaine is a piperidinecarboxamide-based amide-type local anaesthetic (amide caine) in which (S)-N-propylpipecolic acid and 2,6-dimethylaniline are combined to form the amide bond. It has a role as a local anaesthetic. It is a piperidinecarboxamide and a ropivacaine.