CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Boiling Point | 688 |
Melting Point | 240 |
Solubility | In water, 92 mg/L at 25 °C /Estimated/ |
Vapor Pressure | 4.56X10-13 mm Hg at 25 °C /Estimated/ |
LogP | 1.604 |
Henry's Law Constant | Henry's Law constant = 9.5X10-20 atm-cu m/mol at 25 °C /Estimated/ |
Dissociation Constants | 8.13 |
Collision Cross Section | 194.6 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
Other Experimental Properties | White to off-white crystalline powder that melts at approximately 240 °C. It is freely soluble in water, sparingly soluble in alcohol, and practically insoluble in dichloromethane. /Hydrochloride/ |
COMPUTED DESCRIPTORS
Molecular Weight | 389.4 g/mol |
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XLogP3 | 1.7 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 8 |
Exact Mass | 389.20630436 g/mol |
Monoisotopic Mass | 389.20630436 g/mol |
Topological Polar Surface Area | 112 Ų |
Heavy Atom Count | 28 |
Formal Charge | 0 |
Complexity | 511 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Alfuzosin is a monocarboxylic acid amide, a tetrahydrofuranol and a member of quinazolines. It has a role as an antineoplastic agent, an antihypertensive agent and an alpha-adrenergic antagonist.