81403-68-1
Product Name:
Alfuzosin hydrochloride
Formula:
C19H28ClN5O4
Synonyms:
Alfuzosin hydrochloride;N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride;Uroxatral hydrochloride
Inquiry
COMPUTED DESCRIPTORS
| Molecular Weight | 425.9 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 8 |
| Exact Mass | 425.1829821 g/mol |
| Monoisotopic Mass | 425.1829821 g/mol |
| Topological Polar Surface Area | 112 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 511 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Alfuzosin Hydrochloride is the hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing activity. Alfuzosin selectively binds to and antagonizes post-synaptic alpha-1-adrenoreceptors in smooth muscle of the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra, initiating relaxation of smooth muscle and resulting in improvement of urine flow and the symptoms of benign prostatic hyperplasia (BPH). This agent also blocks alpha-1-adrenoreceptors in peripheral vascular smooth muscle, resulting in vasodilatation and a decrease in peripheral vascular resistance.
RELATED SUPPLIERS
KARPSCHEM LABORATORIES PVT. LTD.
1Y
product:Alfuzosin HCl
(RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2- yl)(methyl)amino]propyl]tetrahydrofuran-2-carboxamide hydrochloride 96%