72741-87-8
Product Name:
SWAINSONINE
Formula:
C8H15NO3
Synonyms:
(1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol;(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol;Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | 143-144 °C |
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SAFETY INFORMATION
Signal word | Warning |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
Molecular Weight | 173.21 g/mol |
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XLogP3 | -1.3 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 0 |
Exact Mass | 173.10519334 g/mol |
Monoisotopic Mass | 173.10519334 g/mol |
Topological Polar Surface Area | 63.9 Ų |
Heavy Atom Count | 12 |
Formal Charge | 0 |
Complexity | 176 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Swainsonine is an indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8. It has a role as an antineoplastic agent, an immunological adjuvant, an EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor and a plant metabolite.