CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Melting Point | 280 °C |
Solubility | Very slightly soluble |
Vapor Pressure | 6.8X10-10 mm Hg at 25 °C /Estimated/ |
LogP | 2.4 |
Henry's Law Constant | Henry's Law constant= 2.7X10-13 atm-cu m/mole at 25 °C /Estimated/ |
Other Experimental Properties | Hydroxyl radical reaction rate constant = 2.5X10-11 cu cm/molec-sec at 25 °C /Estimated/ |
SAFETY INFORMATION
Signal word | Warning |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 256.08 g/mol |
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XLogP3 | 1.6 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 0 |
Exact Mass | 254.9966172 g/mol |
Monoisotopic Mass | 254.9966172 g/mol |
Topological Polar Surface Area | 44.7 Ų |
Heavy Atom Count | 16 |
Formal Charge | 0 |
Complexity | 360 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Anagrelide is a 1,5-dihydroimidazo[2,1-]quinazoline having an oxo substituent at the 2-position and chloro substituents at the 6- and 7-positions. It has a role as an anticoagulant, a platelet aggregation inhibitor, an antifibrinolytic drug and a cardiovascular drug.