68291-97-4

Product Name: Zonisamide

Formula: C8H8N2O3S

Synonyms: 1,2-Benzisoxazole-3-methanesulfonamide;AD 810, CI 912;Zonisamide - CAS 68291-97-4 - Calbiochem

Inquiry

CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	Solid
Color/Form	White needles from ethyl acetate
Odor	Odorless
Taste	Tasteless
Melting Point	161-163 °C
Solubility	>31.8 [ug/mL] (The mean of the results at pH 7.4)
Vapor Pressure	3.3X10-6 mm Hg at 25 °C /Estimated/
LogP	0.5
Henry's Law Constant	Henry's Law constant = 4.9X10-11 atm-cu m/mole at 25 °C /Estimated/
Dissociation Constants	10.2
Kovats Retention Index	2022.9
Other Experimental Properties	Hydroxyl radical reaction rate constant = 3.0X10-11 cu cm/molecule sec at 25 °C /Estimated/

SAFETY INFORMATION

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H361:Reproductive toxicity
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.

COMPUTED DESCRIPTORS

Molecular Weight	212.23 g/mol
XLogP3	0.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	212.02556330 g/mol
Monoisotopic Mass	212.02556330 g/mol
Topological Polar Surface Area	94.6 Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	298
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

description

Zonisamide has a role as an anticonvulsant, an antioxidant, a central nervous system drug, a protective agent and a T-type calcium channel blocker. It is a member of 1,2-benzoxazoles and a sulfonamide.