CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | CRYSTALS FROM WATER + ACETONE |
| Melting Point | 195 dec °C |
| Solubility | 10000 mg/L (at 20 °C) |
| LogP | -3.1 |
| Stability/Shelf Life | FREE ACID & ITS SALTS ARE STABLE FOR LONG PERIODS IN DRY STATE; NEUTRAL SOLN ARE ALSO STABLE |
| Optical Rotation | SPECIFIC OPTICAL ROTATION: -26 DEG @ 20 °C/D (C= 2, 10% HCL); & -47.5 DEG @ 20 °C/D (C= 2, 2% NAOH) |
| Dissociation Constants | PK1= 3.8; PK2= 6.2 |
| Collision Cross Section | 171.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)] |
| Other Experimental Properties | MOLAR ABSORBANCY= 15400 @ 259 NM (PH 7.0); READILY DEAMINATED BY NITROUS ACID TO FORM INOSINIC ACID; LESS RAPIDLY HYDROLYZED THAN 3'-ADENYLIC ACID BY SULFURIC ACID |
COMPUTED DESCRIPTORS
| Molecular Weight | 347.22 g/mol |
|---|---|
| XLogP3 | -3.5 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 4 |
| Exact Mass | 347.06308480 g/mol |
| Monoisotopic Mass | 347.06308480 g/mol |
| Topological Polar Surface Area | 186 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 481 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Adenosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. It has a role as an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an adenosine A1 receptor agonist, a nutraceutical, a micronutrient, a fundamental metabolite and a cofactor. It is an adenosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate base of an adenosine 5'-monophosphate(1+). It is a conjugate acid of an adenosine 5'-monophosphate(2-).