60719-84-8
Product Name:
Amrinone
Formula:
C10H9N3O
Synonyms:
5-Amino-(3,4′-bipyridin)-6(1H)-one;Inamrinone
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Melting Point | 294-297 |
Solubility | >28.1 [ug/mL] (The mean of the results at pH 7.4) |
Collision Cross Section | 139 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral |
COMPUTED DESCRIPTORS
Molecular Weight | 187.20 g/mol |
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XLogP3 | -0.2 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 1 |
Exact Mass | 187.074561919 g/mol |
Monoisotopic Mass | 187.074561919 g/mol |
Topological Polar Surface Area | 68 Ų |
Heavy Atom Count | 14 |
Formal Charge | 0 |
Complexity | 301 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Amrinone is a 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure. It has a role as an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor.