552-89-6
Product Name:
2-Nitrobenzaldehyde
Formula:
C7H5NO3
Synonyms:
o-NBA;ortho-nitrobenzaldehyde;2-Nitrobenzaldehyde
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SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
PRODUCT INTRODUCTION
Description
2-Nitrobenzaldehyde (2-NBA) is a widely used organic compound. It reacts with chitosan to form 2-nitrobenzyl chitosan. 2-NBA is also used in the synthesis of acridones. The reaction mechanism involves protonation of benzaldehyde by H2SO4 followed by electrophilic addition to an electron-rich alkyne (benzene). The hydroxyl group formed reacts intramolecularly with ortho nitro groups to form anthranils (3-phenyl-1,2-benzisoxazoles). Anthraquinone is treated with nitrous acid to form N-nitroso acridinone, which finally releases the nitro group to form acridinone.