54-25-1
Product Name:
6-AZAURIDINE
Formula:
C8H11N3O6
Synonyms:
2-β-D -Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione;6-Azauracil riboside
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Crystals from ether, ethanol |
|---|---|
| Melting Point | 158 °C |
| Solubility | 36.2 [ug/mL] (The mean of the results at pH 7.4) |
| LogP | log Kow = -2.14 |
| Optical Rotation | Max absorption (water): 262 nm (e= 6100); specific optical rotation: -132 deg at 24 °C/D (pyridine) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxide/. |
| Dissociation Constants | pKa = 6.63 |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 245.19 g/mol |
|---|---|
| XLogP3 | -2.1 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 245.06478508 g/mol |
| Monoisotopic Mass | 245.06478508 g/mol |
| Topological Polar Surface Area | 132 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 372 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
6-azauridine is a N-glycosyl-1,2,4-triazine. It has a role as an antineoplastic agent, an antimetabolite and a drug metabolite.