520-85-4
Product Name:
MEDROXYPROGESTERONE
Formula:
C22H32O3
Synonyms:
17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione;17α-Hydroxy-6α-methylprogesterone;6α-Methyl-5-pregnen-17α-ol-3,20-dione;6-Dihydromegestrol;Medroxyprogesterone
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Crystals from chloroform |
| Melting Point | 214.5 °C |
| Solubility | Solubility at 25 °C: in acetone 1 in 50; slightly soluble in ether and methanol; sol at 25 °C in dioxane: 1 in 60 /Medoxyprogesteron acetate/ |
| Stability/Shelf Life | Stable in air. /Acetate/ |
| Optical Rotation | Specific optical rotation: +75 deg at 25 °C/D (in chloroform) |
| Decomposition | When heated to decomposition it emits acrid smoke and irritating fumes. |
| Other Experimental Properties | White to off-white, crystalline powder, odorless. Melting range 200-208 °C. Stable in air. Freely soluble in chlorform. /Medroxyprogesterone acetate/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H361:Reproductive toxicity |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
| Molecular Weight | 344.5 g/mol |
|---|---|
| XLogP3 | 3.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 344.23514488 g/mol |
| Monoisotopic Mass | 344.23514488 g/mol |
| Topological Polar Surface Area | 54.4 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 664 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Medroxyprogesterone is a 3-oxo Delta(4)-steroid that is pregn-4-ene-3,20-dione substituted by an alpha-hydroxy group at position 17 and a methyl group at position 6. It has a role as a contraceptive drug, a progestin and a synthetic oral contraceptive. It is a 20-oxo steroid, a 3-oxo-Delta(4) steroid, a 17alpha-hydroxy steroid and a tertiary alpha-hydroxy ketone.