3886-70-2

Product Name: (R)-(+)-1-(1-Naphthyl)ethylamine

Formula: C12H13N

Synonyms: (R)-(+)-α-Methyl-1-naphthalenemethylamine

Inquiry

SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

SAFETY INFORMATION

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight	171.24 g/mol
XLogP3	2.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	171.104799419 g/mol
Monoisotopic Mass	171.104799419 g/mol
Topological Polar Surface Area	26 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	167
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

Description

(R)-(+)-1-(2-Naphthyl)ethylamine, or R-2-NEA, is a chiral primary amine with applications in aldol reaction studies and enzyme interactions. It inhibits cyclooxygenase-2 (COX-2), affecting prostaglandin production, and may also interact with COX-1 and serotonin receptor 5-HT2A. Utilized in drug design and research, R-2-NEA has demonstrated anti-cancer, anti-inflammatory, analgesic, and neuroprotective properties.