CHEMICAL AND PHYSICAL PROPERTIES
Odor | Odorless |
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Taste | Tasteless |
Solubility | WHITE OR ALMOST WHITE, CRYSTALLINE POWDER; SPARINGLY SOL IN ALC; SLIGHTLY SOL IN ETHER & FIXED OILS; SOL IN ACETONE; VERY SOL IN CHLOROFORM /ACETATE/ |
Collision Cross Section | 202.21 Ų [M+Cl]- 198.71 Ų [M+H]+ |
Other Experimental Properties | Crystals. MW: 384.50, mp 214-216 °C. Soluble in water. /Megestrol acetate/ |
COMPUTED DESCRIPTORS
Molecular Weight | 342.5 g/mol |
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XLogP3 | 2.6 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 1 |
Exact Mass | 342.21949481 g/mol |
Monoisotopic Mass | 342.21949481 g/mol |
Topological Polar Surface Area | 54.4 Ų |
Heavy Atom Count | 25 |
Formal Charge | 0 |
Complexity | 717 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 6 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Megestrol is a 3-oxo Delta(4)-steroid that is pregna-4,6-diene-3,20-dione substituted by a methyl group at position 6 and a hydroxy group at position 17. It has a role as a contraceptive drug, an antineoplastic agent, an appetite enhancer, a progestin and a synthetic oral contraceptive. It is a 20-oxo steroid, a 17alpha-hydroxy steroid, a 3-oxo-Delta(4) steroid and a tertiary alpha-hydroxy ketone.