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3382-63-6

3382-63-6 structural image
Product Name: 4-[[(4-Fluorophenyl)imino]methyl]-phenol
Formula: C13H10FNO
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COMPUTED DESCRIPTORS

Molecular Weight 215.22 g/mol
XLogP3 2.6
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 2
Exact Mass 215.074642105 g/mol
Monoisotopic Mass 215.074642105 g/mol
Topological Polar Surface Area 32.6 Ų
Heavy Atom Count 16
Formal Charge 0
Complexity 228
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

Description

4-[[(4-Fluorophenyl)imino]methyl]-phenol is a benzyl ketone, It reacts with propanedithiol in the presence of an alkali to give the cyclized product ezetimibe. This reaction yields the desired product in high yield, but requires an expensive catalyst.

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