21829-25-4
Product Name:
Nifedipine
Formula:
C17H18N2O6
Synonyms:
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester;L-Type Calcium Channel Blocker III;Nifedipine;Nifedipine - CAS 21829-25-4 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Nifedipine appears as odorless yellow crystals or powder. Tasteless. (NTP, 1992) |
|---|---|
| Color/Form | Yellow crystals |
| Melting Point | 342 to 345 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 67.1 °F (NTP, 1992) |
| Vapor Pressure | 2.6X10-8 mm Hg at 25 °C |
| LogP | 2.2 |
| Decomposition | When heated to decomposition, it emits toxic fumes of /nitrogen oxides/. |
| Collision Cross Section | 169.4 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
| Kovats Retention Index | 2536.74 |
| Other Experimental Properties | Very light sensitive in solution |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
COMPUTED DESCRIPTORS
| Molecular Weight | 346.3 g/mol |
|---|---|
| XLogP3 | 2.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 346.11648630 g/mol |
| Monoisotopic Mass | 346.11648630 g/mol |
| Topological Polar Surface Area | 110 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 608 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nifedipine appears as odorless yellow crystals or powder. Tasteless. (NTP, 1992)