158930-17-7
Product Name:
Frova
Formula:
C18H25N3O6
Synonyms:
Frovatriptan succinate;R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate
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COMPUTED DESCRIPTORS
| Molecular Weight | 379.4 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 379.17433553 g/mol |
| Monoisotopic Mass | 379.17433553 g/mol |
| Topological Polar Surface Area | 147 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 426 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 3 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)
RELATED SUPPLIERS
Vepan Pharmatech Pvt Ltd
1Y
product:(3R)-2,3,4,9- tetrahydro-3- (methylamino)1H- carbazole-6- carboxamide. succinate monohydrate, USP