144494-65-5
Product Name:
Tirofiban
Formula:
C22H36N2O5S
Synonyms:
(2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid;N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L -tyrosine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Color/Form | White solid |
Melting Point | 223-225 °C |
Solubility | Very slightly soluble |
Vapor Pressure | 5.2X10-16 mmHg at 25 °C /Estimated/ |
LogP | 1.4 |
Henry's Law Constant | Henry's Law constant = 7.4X10-15 atm-cu m/mole at 25 °C /Estimated/ |
Dissociation Constants | pKa = 3.3 (carboxylic acid); pKa = 10.5 (amine) /Estimated/ |
Other Experimental Properties | White to off-white, non-hygroscopic, free-flowing powder; MW: 495.08; very slightly soluble in water. /Tirofiban hydrochloride salt mono hydrate/ |
SAFETY INFORMATION
Signal word | Warning |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 440.6 g/mol |
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XLogP3 | 1.4 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 14 |
Exact Mass | 440.23449343 g/mol |
Monoisotopic Mass | 440.23449343 g/mol |
Topological Polar Surface Area | 113 Ų |
Heavy Atom Count | 30 |
Formal Charge | 0 |
Complexity | 579 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tirofiban is a member of the class of piperidines that is L-tyrosine in which a hydrogen attached to the amino group is replaced by a butylsulfonyl group and in which the hydrogen attached to the phenolic hydroxy group is replaced by a 4-(piperidin-4-yl)butyl group. It has a role as a fibrin modulating drug, a platelet glycoprotein-IIb/IIIa receptor antagonist and an anticoagulant. It is a member of piperidines, a sulfonamide and a L-tyrosine derivative.
RELATED SUPPLIERS
KARPSCHEM LABORATORIES PVT. LTD.
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product:144494-65-5 Tirofiban
(S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4- yl)butoxy)phenyl)propanoic acid 96%