Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas144060-53-7

144060-53-7

144060-53-7 structural image
Product Name: Febuxostat
Formula: C16H16N2O3S
Synonyms: 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid;Adenuric;Atenuri;Uloric
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Melting Point 238-239°
Solubility <1 mg/mL
Collision Cross Section 180.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

COMPUTED DESCRIPTORS

Molecular Weight 316.4 g/mol
XLogP3 3.9
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 5
Exact Mass 316.08816355 g/mol
Monoisotopic Mass 316.08816355 g/mol
Topological Polar Surface Area 111 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 448
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Febuxostat is a 1,3-thiazolemonocarboxylic acid that is 4-methyl-1,3-thiazole-5-carboxylic acid which is substituted by a 3-cyano-4-(2-methylpropoxy)phenyl group at position 2. It is an orally-active, potent, and selective xanthine oxidase inhibitor used for the treatment of chronic hyperuricaemia in patients with gout. It has a role as an EC 1.17.3.2 (xanthine oxidase) inhibitor. It is an aromatic ether, a nitrile and a 1,3-thiazolemonocarboxylic acid.

RELATED SUPPLIERS

KARPSCHEM LABORATORIES PVT. LTD.

1Y
product:144060-53-7 Febuxostat 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5- carboxylic acid 96%

Metrochem API Private Limited

1Y
product:Febuxostat 98%

Lupin Ltd

1Y
product:Febuxostat 144060-53-7 99%

Apotex Pharmachem India Pvt Ltd

1Y
product:Febuxostat 98%

Alembic Pharmaceuticals Limited

1Y
product:144060-53-7 Febuxostat 98%

Hetero Drugs Limited

1Y
product:144060-53-7 98%

Basic Pharma Life Science Pvt Ltd

1Y
product:Febuxostat 98%

Macleods Pharmaceuticals Limited

1Y
product:Febuxostat 144060-53-7 98%

Everest Organics Limited

1Y
product:144060-53-7 99%
All suppliers(40)