Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas130929-57-6

130929-57-6

130929-57-6 structural image
Product Name: Entacapone
Formula: C14H15N3O5
Synonyms: 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Color/Form Crystals from acetic acid + hydrochloric acid
Melting Point 162-163 °C
LogP 2.8
Stability/Shelf Life Stable under recommended storage conditions.
Dissociation Constants pKa approximately 4.5

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

COMPUTED DESCRIPTORS

Molecular Weight 305.29 g/mol
XLogP3 2.1
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 4
Exact Mass 305.10117059 g/mol
Monoisotopic Mass 305.10117059 g/mol
Topological Polar Surface Area 130 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 500
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Entacapone is a monocarboxylic acid amide that is N,N-diethylprop-2-enamide in which the hydrogen at position 2 is substituted by a cyano group and the hydrogen at the 3E position is substituted by a 3,4-dihydroxy-5-nitrophenyl group. It has a role as an EC 2.1.1.6 (catechol O-methyltransferase) inhibitor, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent. It is a monocarboxylic acid amide, a nitrile, a member of catechols and a member of 2-nitrophenols.

RELATED SUPPLIERS

NEULAND LABS

1Y
product:Entacapone 98%

USV Pvt Ltd

1Y
product:Entacapone 98%

Aurobindo Pharma Limited

1Y
product:Entacapone 130929-57-6 98%

Hetero Drugs Limited

1Y
product:130929-57-6 Entacapone 98%

Macleods Pharmaceuticals Limited

1Y
product:130929-57-6 98%

Arch Pharmalabs Ltd

1Y
product:Entacapone 98%

Ramdev Chemicals Pvt Ltd

1Y
product:Entacapone 130929-57-6 98%

Besil Chem LLP

1Y
product:130929-57-6 Entacapone 98%

Ralington Pharma

1Y
product:130929-57-6 98%
All suppliers(12)