129-74-8
Product Name:
BUCLIZINE, DIHYDROCHLORIDE
Formula:
C28H35Cl3N2
Synonyms:
1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine;1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine hydrochloride;1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine dihydrochloride;Buclina;Longifene
Inquiry
COMPUTED DESCRIPTORS
Molecular Weight | 505.9 g/mol |
---|---|
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 6 |
Exact Mass | 504.186582 g/mol |
Monoisotopic Mass | 504.186582 g/mol |
Topological Polar Surface Area | 6.5 Ų |
Heavy Atom Count | 33 |
Formal Charge | 0 |
Complexity | 514 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 3 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Buclizine dihydrochloride is a hydrochloride salt that is obtained by reaction of buclizine with 2 equivalents of hydrogen chloride. It has a role as a central nervous system depressant, a local anaesthetic, a histamine antagonist, a cholinergic antagonist and an antiemetic. It contains a buclizine(2+).