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103628-46-2

103628-46-2 structural image
Product Name: Sumatriptan
Formula: C14H21N3O2S
Synonyms: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide;Sumatriptan
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CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Melting Point 169-170
Solubility 40.3 [ug/mL] (The mean of the results at pH 7.4)
LogP 0.93
Dissociation Constants 9.5
Collision Cross Section 162.1 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Kovats Retention Index 2730
Other Experimental Properties MW: 413.49; mp 165-166 °C /Sumatriptan succinate/

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Health Hazard
GHS08
GHS Hazard Statements H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P405:Store locked up.
P501:Dispose of contents/container to..…

COMPUTED DESCRIPTORS

Molecular Weight 295.40 g/mol
XLogP3 0.9
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 6
Exact Mass 295.13544809 g/mol
Monoisotopic Mass 295.13544809 g/mol
Topological Polar Surface Area 73.6 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 405
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Sumatriptan is a sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults. It has a role as a serotonergic agonist and a vasoconstrictor agent. It is a sulfonamide and a member of tryptamines. It is functionally related to a N,N-dimethyltryptamine. It is a conjugate acid of a sumatriptan(1+).

RELATED SUPPLIERS

Vepan Pharmatech Pvt Ltd

1Y
product:[3-(2-Dimethylamino- ethyl)-1H-indol-5-yl] -N-methyl- methanesulfonamide

Ipca Laboratories Ltd

1Y
product:103628-46-2 98%

Lakshmi Farmachem

1Y
product:Sumatriptan 98%

Stereokem Pvt Ltd

1Y
product:Sumatriptan 98%

Dayaram Pharma Chem

1Y
product:103628-46-2 Sumatriptan 98%

Synergene Active Ingredients Pvt. Ltd.

1Y
product:103628-46-2 98%

SMS Pharmaceuticals Ltd

1Y
product:Sumatriptan 98%

Rivashaa Agrotech Biopharma Pvt. Ltd.

1Y
product:103628-46-2 Sumatriptan 98%

Ralington Pharma

1Y
product:103628-46-2 98%
All suppliers(14)